Difference between revisions of "PSD pharmaceutical compounds analysis"
From BioUML platform
m (Protected "PSD pharmaceutical compounds analysis": Autogenerated page ([edit=sysop] (indefinite))) |
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;Analysis title | ;Analysis title | ||
| − | :[[File: | + | :[[File:Genome-enhancer-PSD-pharmaceutical-compounds-analysis-icon.png]] PSD pharmaceutical compounds analysis |
;Provider | ;Provider | ||
:[[Biosoft]] | :[[Biosoft]] | ||
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==== Description ==== | ==== Description ==== | ||
| − | + | This method seeks for the optimal combination of molecular targets among input genes that potentially interact with pharmaceutical compounds from a library of known drugs, using information from HumanPSD™ database. | |
==== Parameters: ==== | ==== Parameters: ==== | ||
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* '''Genes table''' – Path to table with genes | * '''Genes table''' – Path to table with genes | ||
* '''Weight column''' (expert) – Genes<nowiki>'</nowiki> weight column name | * '''Weight column''' (expert) – Genes<nowiki>'</nowiki> weight column name | ||
| + | * '''Weight as rank''' (expert) – Use weight column as rank column | ||
* '''Diseases names''' – Names of the diseases | * '''Diseases names''' – Names of the diseases | ||
| + | * '''False positive target weight''' (expert) – Weight of false positive targets in target activity score formula. False positive targets are known targets of the drug that are not included in input targets list | ||
* '''Output table with structures''' – Output table with structures | * '''Output table with structures''' – Output table with structures | ||
* '''Output table with targets''' – Output table with targets | * '''Output table with targets''' – Output table with targets | ||
Latest revision as of 18:15, 9 December 2020
- Analysis title
PSD pharmaceutical compounds analysis
- Provider
- Biosoft
- Class
PSDPCAnalysis- Plugin
- biouml.plugins.genomeenhancer (Genome Enhancer)
[edit] Description
This method seeks for the optimal combination of molecular targets among input genes that potentially interact with pharmaceutical compounds from a library of known drugs, using information from HumanPSD™ database.
[edit] Parameters:
- Genes table – Path to table with genes
- Weight column (expert) – Genes' weight column name
- Weight as rank (expert) – Use weight column as rank column
- Diseases names – Names of the diseases
- False positive target weight (expert) – Weight of false positive targets in target activity score formula. False positive targets are known targets of the drug that are not included in input targets list
- Output table with structures – Output table with structures
- Output table with targets – Output table with targets
