Mapping to ontology - select a classification (Gene table) (workflow)

From BioUML platform
Jump to: navigation, search
Workflow title
Mapping to ontology - select a classification (Gene table)
Provider
geneXplain GmbH

Workflow overview

Mapping-to-ontology-select-a-classification-Gene-table-workflow-overview.png

Description

 This workflow is designed to map one input tables to one selected ontology classification. The input can be any gene or protein table. In the first step, the input table is converted into one table with Ensembl Gene IDs. The table with Ensembl Gene ID is subjected to functional classification based on the classification option selected in the input field.

The output consists of a folder which stores the mapped classification table. Each output table consists of many columns. The column ID comprises the identifiers of the ontological categories, here identifiers of Gene Ontology biological process terms. These identifiers are hyperlinked to the page http://www.ebi.ac.uk/QuickGO/ where you can get further information about this ontological term.

The columns Title and Group size contain further details about the ontological terms, its title and the number of genes linked to this term in the corresponding database, here in GO. The column Expected hits shows the number of genes expected to fall into this category by random chance, based on the size of the input set and the size of the category. The column Number of hits shows how many genes from the input table fall into this category. P-value and Adjusted P-value are calculated for the difference between expected and real numbers of hits. The genes mapped to each category are explicitly listed in the column Hit names.

 

Parameters

Input table
Species
classification
Result folder
Personal tools
Namespaces

Variants
Actions
BioUML platform
Community
Modelling
Analysis & Workflows
Collaborative research
Development
Virtual biology
Wiki
Toolbox