Difference between revisions of "Patient-specific cardiovascular model"
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! rowspan = "2" |Parameters !! colspan = "3" |Correlations !! colspan="3" |Mean relative error | ! rowspan = "2" |Parameters !! colspan = "3" |Correlations !! colspan="3" |Mean relative error | ||
|- | |- | ||
| − | + | !|Ps||Pd||Pp||Ps||Pd||Pp | |
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!! colspan = "7" |With personalization of TPR | !! colspan = "7" |With personalization of TPR | ||
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! rowspan = "2" |Parameters !! colspan = "3" |Correlations !! colspan="3" |Mean relative error | ! rowspan = "2" |Parameters !! colspan = "3" |Correlations !! colspan="3" |Mean relative error | ||
|- | |- | ||
| − | + | !Ps||Pd||Pp||Ps||Pd||Pp | |
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!! colspan = "7" |a. brachialis dextra | !! colspan = "7" |a. brachialis dextra | ||
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|R SV HR||0,8171||0,8171||-0,120||0,051||0,164||0,205 | |R SV HR||0,8171||0,8171||-0,120||0,051||0,164||0,205 | ||
|- | |- | ||
| − | |a. tibialis posterior sinistra | + | !! colspan = "7" |a. tibialis posterior sinistra |
|- | |- | ||
|R A0 β SV HR||0,6661||0,6441||0,0912||0,246||0,095||0,493 | |R A0 β SV HR||0,6661||0,6441||0,0912||0,246||0,095||0,493 | ||
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|R SV HR||0,5721||0,6401||-0,001||0,187||0,093||0,346 | |R SV HR||0,5721||0,6401||-0,001||0,187||0,093||0,346 | ||
|- | |- | ||
| − | |a. tibialis posterior dextra | + | !! colspan = "7" |a. tibialis posterior dextra |
|- | |- | ||
|R A0 β SV HR||0,6161||0,6261||0,0872||0,248||0,098||0,492 | |R A0 β SV HR||0,6161||0,6261||0,0872||0,248||0,098||0,492 | ||
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! rowspan = "2" |Allometric equation !! colspan = "3" |Correlations !! colspan="3" |Mean relative error | ! rowspan = "2" |Allometric equation !! colspan = "3" |Correlations !! colspan="3" |Mean relative error | ||
|- | |- | ||
| − | + | !|Ps||Pd||Pp||Ps||Pd||Pp | |
|- | |- | ||
|0,7691||0,8481||-0,0002||0,054||0,199||0,343 | |0,7691||0,8481||-0,0002||0,054||0,199||0,343 | ||
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! rowspan = "2" |Model time !! colspan = "3" |Correlations !! colspan="3" |Mean relative error | ! rowspan = "2" |Model time !! colspan = "3" |Correlations !! colspan="3" |Mean relative error | ||
|- | |- | ||
| − | + | !|Ps||Pd||Pp||Ps||Pd||Pp | |
|- | |- | ||
|6 секунд||0,7531||0,8671||0,031||0,058||0,197||0,364 | |6 секунд||0,7531||0,8671||0,031||0,058||0,197||0,364 | ||
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! rowspan = "2" |Age !! #!!colspan = "3" |Correlations !! colspan="3" |Mean relative error | ! rowspan = "2" |Age !! #!!colspan = "3" |Correlations !! colspan="3" |Mean relative error | ||
|- | |- | ||
| − | + | !|Ps||Pd||Pp||Ps||Pd||Pp | |
|- | |- | ||
|<=30||24||0,9441||0,9641||0,257||0,043||0,195||0,306 | |<=30||24||0,9441||0,9641||0,257||0,043||0,195||0,306 | ||
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! rowspan = "2" |Observation date !! #!!colspan = "3" |Correlations !! colspan="3" |Mean relative error | ! rowspan = "2" |Observation date !! #!!colspan = "3" |Correlations !! colspan="3" |Mean relative error | ||
|- | |- | ||
| − | + | !|Ps||Pd||Pp||Ps||Pd||Pp | |
|- | |- | ||
|Before 01.05.1999||420||0,7331||0,8011||0,1112||0,073||0,199||0,335 | |Before 01.05.1999||420||0,7331||0,8011||0,1112||0,073||0,199||0,335 | ||
Latest revision as of 15:08, 25 September 2015
This page was created to support article "Patient-specific model of the human cardiovascular system" sumbitted to 2015 International Conference on Biomedical Engineering and Computational Technologies SIBIRCON.
Article describes personalization procedure of 1-dimensional arterial tree model validated against a set of data on ~1200 individuals.
For personalization procedure model was updated with 4 new vessels and new function for input blood flow calculations. This version of the model is available here.
[edit] Simulation results
Table 1. Simulation results for a. brachialis sinistra (left brachial artery)
| Parameters | Correlations | Mean relative error | ||||
|---|---|---|---|---|---|---|
| Ps | Pd | Pp | Ps | Pd | Pp | |
| With personalization of TPR | ||||||
| TPR A0 β SV HR | 0,7841 | 0,8641 | 0,011 | 0,055 | 0,208 | 0,372 |
| TPR SV HR | 0,8971 | 0,9251 | -0,070 | 0,041 | 0,164 | 0,283 |
| TPR HR | 0,4841 | 0,5561 | -0,3182 | 0,169 | 0,391 | 0,214 |
| TPR SV | 0,4221 | 0,5301 | -0,075 | 0,119 | 0,249 | 0,283 |
| TPR A0β | 0,6931 | 0,7811 | 0,006 | 0,158 | 0,472 | 0,328 |
| TPR A0 | 0,5691 | 0,8381 | -0,1252 | 0,209 | 0,385 | 0,285 |
| TPR β | 0,8061 | 0,7591 | 0,0852 | 0,123 | 0,486 | 0,400 |
| TPR | 0,8101 | 0,8381 | -0,4011 | 0,164 | 0,425 | 0,210 |
| Without personalization iof TPR | ||||||
| A0 β SV HR | 0,007 | -0,1621 | 0,046 | 0,171 | 0,126 | 0,342 |
| SV HR | -0,060 | -0,012 | 0,014 | 0,165 | 0,129 | 0,253 |
| HR | 0,034 | 0,077 | -0,020 | 0,122 | 0,189 | 0,177 |
| SV | -0,035 | -0,073 | 0,019 | 0,167 | 0,161 | 0,252 |
| A0 β | 0,080 | -0,226 | 0,051 | 0,092 | 0,181 | 0,301 |
| A0 | -0,1451 | 0,1501 | -0,0922 | 0,113 | 0,120 | 0,283 |
| β | 0,2941 | -0,2971 | 0,1372 | 0,086 | 0,195 | 0,365 |
Table 2. Simulation results for right brachial arterty and lower limbs. In total – 556 individuals
| Parameters | Correlations | Mean relative error | ||||
|---|---|---|---|---|---|---|
| Ps | Pd | Pp | Ps | Pd | Pp | |
| a. brachialis dextra | ||||||
| R A0 β SV HR | 0,6811 | 0,7531 | -0,0452 | 0,064 | 0,202 | 0,288 |
| R SV HR | 0,8171 | 0,8171 | -0,120 | 0,051 | 0,164 | 0,205 |
| a. tibialis posterior sinistra | ||||||
| R A0 β SV HR | 0,6661 | 0,6441 | 0,0912 | 0,246 | 0,095 | 0,493 |
| R SV HR | 0,5721 | 0,6401 | -0,001 | 0,187 | 0,093 | 0,346 |
| a. tibialis posterior dextra | ||||||
| R A0 β SV HR | 0,6161 | 0,6261 | 0,0872 | 0,248 | 0,098 | 0,492 |
| R SV HR | 0,5681 | 0,6501 | -0,026 | 0,193 | 0,087 | 0,375 |
Table 3. Simulation results for different allometric equations used for minute output. All parameters were personalized: R, A0, β, SV, HR. In total – 556 individuals
| Allometric equation | Correlations | Mean relative error | ||||
|---|---|---|---|---|---|---|
| Ps | Pd | Pp | Ps | Pd | Pp | |
| 0,7691 | 0,8481 | -0,0002 | 0,054 | 0,199 | 0,343 | |
| 0,7501 | 0,8311 | -0,015 | 0,056 | 0,192 | 0,328 | |
| 0,7821 | 0,8641 | 0,011 | 0,055 | 0,208 | 0,372 | |
| 0,7591 | 0,8421 | -0,006 | 0,055 | 0,197 | 0,338 | |
Table 4. Simulation results with different model time. In each simulation last 2 seconds were used to obserev minimal and maximal ressures produced by the model
| Model time | Correlations | Mean relative error | ||||
|---|---|---|---|---|---|---|
| Ps | Pd | Pp | Ps | Pd | Pp | |
| 6 секунд | 0,7531 | 0,8671 | 0,031 | 0,058 | 0,197 | 0,364 |
| 12 секунд | 0,7841 | 0,8641 | 0,011 | 0,055 | 0,208 | 0,372 |
| 20 секунд | 0,7891 | 0,8621 | 0,008 | 0,055 | 0,209 | 0,373 |
Table 5. Simulation results for different age groups. Only TPR was personalized.
| Age | # | Correlations | Mean relative error | ||||
|---|---|---|---|---|---|---|---|
| Ps | Pd | Pp | Ps | Pd | Pp | ||
| <=30 | 24 | 0,9441 | 0,9641 | 0,257 | 0,043 | 0,195 | 0,306 |
| (30,50] | 42 | 0,8421 | 0,8841 | 0,121 | 0,032 | 0,152 | 0,231 |
| (50,60] | 178 | 0,8921 | 0,9371 | -0,003 | 0,036 | 0,152 | 0,247 |
| (60,70] | 246 | 0,9081 | 0,9311 | -0,010 | 0,040 | 0,162 | 0,289 |
| (70,80] | 181 | 0,8771 | 0,8961 | -0,137 | 0,051 | 0,171 | 0,307 |
Table 6. Simulation results for control group (observation were recorded before 1 of May 1999)
| Observation date | # | Correlations | Mean relative error | ||||
|---|---|---|---|---|---|---|---|
| Ps | Pd | Pp | Ps | Pd | Pp | ||
| Before 01.05.1999 | 420 | 0,7331 | 0,8011 | 0,1112 | 0,073 | 0,199 | 0,335 |
| After 01.05.1999 | 556 | 0,7841 | 0,8641 | 0,011 | 0,055 | 0,208 | 0,372 |
| Any | 976 | 0,7541 | 0,8361 | 0,098 | 0,062 | 0,205 | 0,356 |
