PSD pharmaceutical compounds analysis

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Analysis title
Genome-enhancer-PSD-pharmaceutical-compounds-analysis-icon.png PSD pharmaceutical compounds analysis
Provider
Biosoft
Class
PSDPCAnalysis
Plugin
biouml.plugins.genomeenhancer (Genome Enhancer)

Description

This method seeks for the optimal combination of molecular targets among input genes that potentially interact with pharmaceutical compounds from a library of known drugs, using information from HumanPSD™ database.

Parameters:

  • Genes table – Path to table with genes
  • Weight column (expert) – Genes' weight column name
  • Weight as rank (expert) – Use weight column as rank column
  • Diseases names – Names of the diseases
  • False positive target weight (expert) – Weight of false positive targets in target activity score formula. False positive targets are known targets of the drug that are not included in input targets list
  • Output table with structures – Output table with structures
  • Output table with targets – Output table with targets
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