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		<title>Mutation effect on sites advanced (analysis) - Revision history</title>
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		<updated>2026-04-13T03:19:53Z</updated>
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				<updated>2020-12-09T11:14:52Z</updated>
		
		<summary type="html">&lt;p&gt;Protected &amp;quot;&lt;a href=&quot;/index.php/Mutation_effect_on_sites_advanced_(analysis)&quot; title=&quot;Mutation effect on sites advanced (analysis)&quot;&gt;Mutation effect on sites advanced (analysis)&lt;/a&gt;&amp;quot;: Autogenerated page (‎[edit=sysop] (indefinite))&lt;/p&gt;
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			&lt;td colspan='1' style=&quot;background-color: white; color:black;&quot;&gt;← Older revision&lt;/td&gt;
			&lt;td colspan='1' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 11:14, 9 December 2020&lt;/td&gt;
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		<author><name>WikiBot</name></author>	</entry>

	<entry>
		<id>https://wiki.biouml.org/index.php?title=Mutation_effect_on_sites_advanced_(analysis)&amp;diff=8790&amp;oldid=prev</id>
		<title>WikiBot: Automatic synchronization with BioUML</title>
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				<updated>2020-12-09T11:14:52Z</updated>
		
		<summary type="html">&lt;p&gt;Automatic synchronization with BioUML&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;;Analysis title&lt;br /&gt;
:[[File:GTRD-Mutation-effect-on-sites-advanced-icon.png]] Mutation effect on sites advanced&lt;br /&gt;
;Provider&lt;br /&gt;
:[[Institute of Systems Biology]]&lt;br /&gt;
;Class&lt;br /&gt;
:{{Class|biouml.plugins.gtrd.analysis.maos.MutationAffectOnSitesAdvanced}}&lt;br /&gt;
;Plugin&lt;br /&gt;
:[[Biouml.plugins.gtrd (plugin)|biouml.plugins.gtrd (GTRD)]]&lt;br /&gt;
&lt;br /&gt;
==== Parameters: ====&lt;br /&gt;
&lt;br /&gt;
* '''Input VCF track''' – Input track in VCF format&lt;br /&gt;
* '''Genome''' – Reference genome&lt;br /&gt;
** '''Sequences source''' – Select database to get sequences from or &amp;lt;nowiki&amp;gt;'&amp;lt;/nowiki&amp;gt;Custom&amp;lt;nowiki&amp;gt;'&amp;lt;/nowiki&amp;gt; to specify sequences location manually&lt;br /&gt;
** '''Sequence collection''' – Specify path to folder containing sequences if &amp;lt;nowiki&amp;gt;'&amp;lt;/nowiki&amp;gt;Custom&amp;lt;nowiki&amp;gt;'&amp;lt;/nowiki&amp;gt; sequences source is selected&lt;br /&gt;
* '''Profile''' – Predefined set of site models&lt;br /&gt;
* '''Score type''' – The type of position weight matrix score&lt;br /&gt;
* '''Score difference''' – Minimal site score difference between reference and alternative sequences&lt;br /&gt;
* '''Independent variations''' – Treat each variation independently&lt;br /&gt;
* '''Target gene TSS upstream''' – When searching for target genes, match TF binding sites to this distance upstream of TSS.&lt;br /&gt;
* '''Target gene TSS downstream''' – When searching for target genes, match TF binding sites to this distance downstream of TSS.&lt;br /&gt;
* '''One nearest target gene''' – Report only one target gene nearest to TSS.&lt;br /&gt;
* '''TF class depth''' – TF class depth&lt;br /&gt;
* '''Add transpath annotation''' – Transpath pathways annotation will be added to the output table&lt;br /&gt;
* '''Transpath''' – Transpath&lt;br /&gt;
* '''Add HumanPSD annotation''' – HumanPSD disease annotation will be added to the output table&lt;br /&gt;
* '''HumanPSD''' – HumanPSD&lt;br /&gt;
* '''Output table''' – Output table&lt;br /&gt;
* '''Site gain track''' – Resulting track with site gain events&lt;br /&gt;
* '''Site loss track''' – Resulting track with site gain events&lt;br /&gt;
* '''Important mutations''' – Track of mutations that affects binding sites&lt;br /&gt;
* '''Summary table''' – Summary table giving site model frequencies per mutation&lt;br /&gt;
* '''Selected GTRD peaks/metaclusters''' – Selected GTRD peaks/metaclusters&lt;br /&gt;
&lt;br /&gt;
[[Category:Analyses]]&lt;br /&gt;
[[Category:GTRD (analyses group)]]&lt;br /&gt;
[[Category:ISB analyses]]&lt;br /&gt;
[[Category:Autogenerated pages]]&lt;/div&gt;</summary>
		<author><name>WikiBot</name></author>	</entry>

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