https://wiki.biouml.org/index.php?action=history&feed=atom&title=Find_10_master_regulators_in_networks_%28TRANSPATH%28R%29%29_%28workflow%29 2026-04-12T21:47:18Z Revision history for this page on the wiki MediaWiki 1.20.3 https://wiki.biouml.org/index.php?title=Find_10_master_regulators_in_networks_(TRANSPATH(R))_(workflow)&diff=7120&oldid=prev 2017-02-13T12:02:41Z

<p>Protected &quot;<a href="/index.php/Find_10_master_regulators_in_networks_(TRANSPATH(R))_(workflow)" title="Find 10 master regulators in networks (TRANSPATH(R)) (workflow)">Find 10 master regulators in networks (TRANSPATH(R)) (workflow)</a>&quot;: Autogenerated page (‎[edit=sysop] (indefinite))</p> <table class='diff diff-contentalign-left'> <tr style='vertical-align: top;'> <td colspan='1' style="background-color: white; color:black;">← Older revision</td> <td colspan='1' style="background-color: white; color:black;">Revision as of 12:02, 13 February 2017</td> </tr></table>

WikiBot https://wiki.biouml.org/index.php?title=Find_10_master_regulators_in_networks_(TRANSPATH(R))_(workflow)&diff=7108&oldid=prev 2017-02-13T12:02:25Z

<p>Automatic synchronization with BioUML</p> <p><b>New page</b></p><div>;Workflow title<br /> :Find 10 master regulators in networks (TRANSPATH(R))<br /> ;Provider<br /> :[[geneXplain GmbH]]<br /> == Workflow overview ==<br /> [[File:Find-10-master-regulators-in-networks-TRANSPATH-R-workflow-overview.png|400px]]<br /> == Description ==<br /> '''Variant of the workflow:<br /> <br /> Visualization of top 10 master regular networks, instead of 3 in our &quot;standard&quot; workflows'''<br /> <br /> This workflow is designed to find master regulatory molecules upstream of an input list of genes. Input file is any gene or protein table.<br /> <br />  At the first step, the input table is converted into a table with TRANSPATH® peptides.<br /> <br /> This table is subjected to master regulator search in the TRANSPATH® network. For each potential master regulator, FDR, Score, and Z-score are calculated.<br /> <br /> The results are filtered by Z_Score&gt;1 and Score&gt;0.2 to select statistically significant master regulators.<br /> <br /> Further, the filtered regulatory molecules are converted to both Ensembl Gene IDs and a list of UniProt protein IDs.<br /> <br /> The table with Ensembl Gene Ids is annotated with additional information, gene description and gene symbols.<br /> <br /> Finally, the table with master regulatory molecules is sorted by Score and networks for the three top master regulators are visualized as diagrams in the hierarchical layout.<br /> <br /> This workflow is available together with a valid TRANSPATH® license.<br /> <br /> == Parameters ==<br /> ;Input gene set<br /> ;Species<br /> ;Max steps<br /> :Select max number of steps upstream<br /> ;Results folder<br /> <br /> [[Category:Workflows]]<br /> [[Category:GeneXplain workflows]]<br /> [[Category:Autogenerated pages]]</div>

WikiBot