https://wiki.biouml.org/index.php?action=history&feed=atom&title=Analyze_miRNA_target_enrichment_%28analysis%29 2026-04-21T05:07:48Z Revision history for this page on the wiki MediaWiki 1.20.3 https://wiki.biouml.org/index.php?title=Analyze_miRNA_target_enrichment_(analysis)&diff=8702&oldid=prev 2020-12-09T11:14:35Z

<p>Protected &quot;<a href="/index.php/Analyze_miRNA_target_enrichment_(analysis)" title="Analyze miRNA target enrichment (analysis)">Analyze miRNA target enrichment (analysis)</a>&quot;: Autogenerated page (‎[edit=sysop] (indefinite))</p> <table class='diff diff-contentalign-left'> <tr style='vertical-align: top;'> <td colspan='1' style="background-color: white; color:black;">← Older revision</td> <td colspan='1' style="background-color: white; color:black;">Revision as of 11:14, 9 December 2020</td> </tr></table>

WikiBot https://wiki.biouml.org/index.php?title=Analyze_miRNA_target_enrichment_(analysis)&diff=8698&oldid=prev 2020-12-09T11:14:34Z

<p>Automatic synchronization with BioUML</p> <p><b>New page</b></p><div>;Analysis title<br /> :[[File:BSA-Analyze-miRNA-target-enrichment-icon.png]] Analyze miRNA target enrichment<br /> ;Provider<br /> :[[geneXplain GmbH]]<br /> ;Class<br /> :{{Class|com.genexplain.mirna.MirnaTargetAnalyzer}}<br /> ;Plugin<br /> :[[Com.genexplain.mirna (plugin)|com.genexplain.mirna (geneXplain micro-RNA)]]<br /> <br /> === Analyze micro-RNA target enrichment ===<br /> <br /> ==== Parameters ====<br /> <br /> * '''Input genes''' - Genes to analyze for miRNA target enrichment<br /> * '''Input gene species''' - Species of input genes<br /> * '''miRNA/gene database''' - Database of miRNA/target gene links<br /> * '''miRNA species''' - Report miRNAs with specified species<br /> * '''FDR cutoff''' - Filter output table by FDR<br /> * '''Output path''' - Path for analysis results<br /> <br /> ==== Output ====<br /> <br /> The output is a table of micro-RNAs showing their enrichment in the set of input genes. The result table comprises the number of input genes with at least one miRNA site, the adjusted fold enrichment, the P-value of enrichment, the FDR of enrichment, the score cutoff with best enrichment, and the gene hits satisfying the best score cutoff.<br /> <br /> The fold enrichment shows how much more frequent target genes for a miRNA are in the input gene set versus the entire set of database genes. Enrichment is further quantified by P-value (Fisher test) and FDR (Benjamini-Hochberg method).<br /> <br /> The score is database specific, e.g. can be the TargetScan context score or the miRDB SVM score.<br /> <br /> ==== Description ====<br /> This tool takes a set of Ensembl genes and a database of miRNA/target gene links as input and tests for enrichment of micro-RNA targets in the input genes.<br /> [[Category:Analyses]]<br /> [[Category:BSA (analyses group)]]<br /> [[Category:GeneXplain analyses]]<br /> [[Category:Autogenerated pages]]</div>

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